INPROTEOLYS

Proteasome Structure, Function and Interactions

Mechanistic aspects of protein degradation by the ubiquitin-proteasome system. Structure of Proteasome subcomplexes. The importance of proteolysis in homeostasis and regulation of the proteome. Proteomic analysis of `the ubiquitin-landscape` and the Ubiquitinome. The role of the COP9 signalosome in mediating protein degradation in budding yeast. Participation of ubiquitination and protein degradation in mitochondria function and dynamics.

Michael H. Glickman

Oded Kleifeld

Dasha Krutauz

Nurit Livnat-Levanon

Noa Reis

Rina Rosenzeig

Zanlin Yu

Inbal Ziv

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