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| José González Castaño |
| Beatriz Castelao Alvarez |
| Fernando Castelao Losada |
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| E-mail |
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joseg.castano@uam.es |
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| Phone |
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34-914975427 |
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| Fax |
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34-91-5854401 |
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| Address |
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Departamento de Bioquímica. Lab B-13. Facultad de Medicina UAM |
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| Center |
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Universidad Autónoma de Madrid |
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| Group Web |
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| Research Lines |
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| Patents |
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| Publications |
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| Pubmed ID: 17403672 |
| Title: Constitutive/hypoxic degradation of HIF-alpha proteins by the proteasome is independent of von Hippel Lindau protein ubiquitylation and the transactivation activity of the protein. |
| Authors: Xianguo Kong , Beatriz Alvarez-Castelao , Zhao Lin , José G Castaño , Jaime Caro , |
| Year: 2007 |
| Journal: J Biol Chem volume: 282 pages: 15498-505 |
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| Pubmed ID: 17490436 |
| Title: Infection with Salmonella typhimurium has no effect on the composition and cleavage specificity of the 20S proteasome in human lymphoid cells. |
| Authors: Miguel Marcilla , José Antonio López de Castro , José G Castaño , Iñaki Alvarez , |
| Year: 2007 |
| Journal: Immunology volume: 122 pages: 131-9 |
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| Pubmed ID: 16787406 |
| Title: Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain. |
| Authors: Miguel Díaz-Hernández , Adriana G Valera , María A Morán , Pilar Gómez-Ramos , Beatriz Alvarez-Castelao , José G Castaño , Félix Hernández , José J Lucas , |
| Year: 2006 |
| Journal: J Neurochem volume: 98 pages: 1585-96 |
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| Pubmed ID: 16098527 |
| Title: Mechanism of direct degradation of IkappaBalpha by 20S proteasome. |
| Authors: Beatriz Alvarez-Castelao , José G Castaño , |
| Year: 2005 |
| Journal: FEBS Lett volume: 579 pages: 4797-802 |
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| Pubmed ID: 16051267 |
| Title: Generation of DNA double-strand breaks by two independent enzymatic activities in nuclear extracts. |
| Authors: Miguel G Blanco , Francisco Boán , Paula Barros , José G Castaño , Jaime Gómez-Márquez , |
| Year: 2005 |
| Journal: J Mol Biol volume: 351 pages: 995-1006 |
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| Pubmed ID: 15466467 |
| Title: alpha-Synuclein expression levels do not significantly affect proteasome function and expression in mice and stably transfected PC12 cell lines. |
| Authors: Begoña Martìn-Clemente , Beatriz Alvarez-Castelao , Isabel Mayo , Ana Belén Sierra , Virginia Dìaz , Miguel Milán , Isabel Fariñas , Teresa Gómez-Isla , Isidro Ferrer , José G Castaño , |
| Year: 2004 |
| Journal: J Biol Chem volume: 279 pages: 52984-90 |
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| Pubmed ID: 15198127 |
| Title: Proteasomal expression, induction of immunoproteasome subunits, and local MHC class I presentation in myofibrillar myopathy and inclusion body myositis. |
| Authors: Isidro Ferrer , Begoña Martín , José G Castaño , José J Lucas , Dolores Moreno , Montse Olivé , |
| Year: 2004 |
| Journal: J Neuropathol Exp Neurol volume: 63 pages: 484-98 |
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| Pubmed ID: 14684867 |
| Title: Neuronal induction of the immunoproteasome in Huntington's disease. |
| Authors: Miguel Díaz-Hernández , Félix Hernández , Ester Martín-Aparicio , Pilar Gómez-Ramos , María A Morán , José G Castaño , Isidro Ferrer , Jesús Avila , José J Lucas , |
| Year: 2003 |
| Journal: J Neurosci volume: 23 pages: 11653-61 |
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| Pubmed ID: 14517305 |
| Title: The COOH-terminal domain of wild-type Cot regulates its stability and kinase specific activity. |
| Authors: Maria Luisa Gándara , Pilar López , Raquel Hernando , José G Castaño , Susana Alemany , |
| Year: 2003 |
| Journal: Mol Cell Biol volume: 23 pages: 7377-90 |
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| Pubmed ID: 12429593 |
| Title: The proteasome is a major autoantigen in multiple sclerosis. |
| Authors: Isabel Mayo , Joaquín Arribas , Pablo Villoslada , Rita Alvarez DoForno , Susana Rodríguez-Vilariño , Xavier Montalban , María Rosa De Sagarra , José G Castaño , |
| Year: 2002 |
| Journal: Brain volume: 125 pages: 2658-67 |
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| Pubmed ID: 12181345 |
| Title: Clastosome: a subtype of nuclear body enriched in 19S and 20S proteasomes, ubiquitin, and protein substrates of proteasome. |
| Authors: Miguel Lafarga , Maria Teresa Berciano , Emma Pena , Isabel Mayo , Jose G Castaño , Dirk Bohmann , João Pedro Rodrigues , João Paulo Tavanez , Maria Carmo-Fonseca , |
| Year: 2002 |
| Journal: Mol Biol Cell volume: 13 pages: 2771-82 |
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| Pubmed ID: 12007144 |
| Title: Proteasome dynamics during cell cycle in rat Schwann cells. |
| Authors: Miguel Lafarga , Rosario Fernández , Isabel Mayo , María T Berciano , José G Castaño , |
| Year: 2002 |
| Journal: Glia volume: 38 pages: 313-28 |
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| Pubmed ID: 11059856 |
| Title: Antibodies against the COOH-terminal region of E. coli ClpP protease in patients with primary biliary cirrhosis. |
| Authors: I Mayo , P Arizti , A Parés , J Oliva , R A Doforno , M R de Sagarra , J Rodés , J G Castaño , |
| Year: 2000 |
| Journal: J Hepatol volume: 33 pages: 528-36 |
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| Pubmed ID: 11007884 |
| Title: Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy. |
| Authors: K B Kegel , M Kim , E Sapp , C McIntyre , J G Castaño , N Aronin , M DiFiglia , |
| Year: 2000 |
| Journal: J Neurosci volume: 20 pages: 7268-78 |
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| Pubmed ID: 10692467 |
| Title: Proteolytic processing and assembly of the C5 subunit into the proteasome complex. |
| Authors: S Rodriguez-Vilariño , J Arribas , P Arizti , J G Castaño , |
| Year: 2000 |
| Journal: J Biol Chem volume: 275 pages: 6592-9 |
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| Keywords |
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proteolysis, Transcription factors, ubiquitin, proteasome, Park genes, Parkinson Disease, synuclein |
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