Past Events 2011 |
|
|
 |
Register here:
http://www.fundacioncac.es/eng/fundacion/actividades/actividadesficha.jsp?idActividad=119 |
Intracellular Proteolysis
and Cancer
From basic research to patient care
( 6th INPROTEOLYS meeting)
|
|
Valencia, Spain - October 26th-28th, 2011
PRELIMINARY PROGRAMME
Session I: Proteases and Cancer
• Carlos López-Otín. Instituto Universitario de Oncología, Universidad de Oviedo. Oviedo. Spain.
Autophagy, proteases and tumour suppression
• Joaquín Arribas. Medical Oncology Research Program, Vall d'Hebron Institute of Oncology. Barcelona. Spain
Proteolytic remodeling of the cell surface during breast cancer progression and treatment
• Bonnie F. Sloane. Dept. of Pharmacology and Karmanos Cancer Institute, Wayne State University School of Medicine. Detroit, MI, USA.
Tumor-Stromal Proteolysis: Now Playing in 4D
• Sharad Kumar. Dept. of Haematology, SA Pathology, Centre for Cancer Biology. Adelaide, Australia.
Caspase-2 function in tumour suppression and aging
Session II: Ubiquitin Proteasome System and Cancer
• Martin Scheffner. Dept. of Biology, University of Konstanz. Konstanz, Germany.
Cellular and viral oncoproteins - substrates and components of the ubiquitin-proteasome system
• R. John Mayer. University of Nottingham Medical School, Queen's Medical Centre. Nottingham, UK.
Gankyrin: a promiscous oncoprotein and regulator of the 26S proteasome
• Brenda Schulman. St. Jude Children's Research Hospital, Memphis, TN, USA.
Structural insights into cullin-RING E3 ligases
• Alfred L. Goldberg. Harvard Medical School. Boston, MA, USA.
New insights into proteasome function in normal and disease dtates
Session III: Ubiquitin Proteasome System, Cell Cycle
and Cancer
• Marcos Malumbres. Cell division and Cancer group, Centro Nacional de Investigaciones Oncológicas. Madrid. Spain.
The anaphase-promoting complex and mitotic exit in mammals: implications in proliferation, differentiation and cancer therapy
• Michele Pagano. Dept. of Pathology, New York University School of Medicine. NY, USA.
Deregulation of SCF ubiquitin ligases in cancer cells
• Tony Hunter. Salk Instittute, San Diego, CA, USA.
Signal transduction in DNA damage and cancer
• Jiri Bartek. Institute of Cancer Biology, Danish Cancer Society, Copenhagen, Denmark.
DNA damage response and cancer: Mechanisms and impact on personalized therapy
Session IV: Ubiquitin Proteasome System, Cell Signalling
and Cancer
• Michael Karin. University of California. San Diego, CA, USA.
Selective ubiquitination determines specificity in innate immune signaling
• Píer Paolo Di Fiore. Fondazione IFOM-Istituto FIRC di Oncologia Molecolare. Milan, Italy.
Endocytosis, stem cells and cancer
• Ze’ev Ronai. NCI Cancer Center, Sanford-Burnham Institute. La Jolla, CA, USA
Siah in hypoxia and cancer
Session V: Ubiquitin-like and Cancer
• Ronald Hay. Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee. Dundee, UK.
How SUMO targets proteins for ubiquitin mediated proteolysis
• Anne Dejean. Institut Pasteur. Paris, France.
Role of sumoylation in normal and pathological processes
Session V: Drug Discovery and Cancer Therapeutics
• James C. Cusack. Massachusetts General Hospital, MA, USA.
Targeting the proteasome in solid organ malignancy-an adjunct to conventional therapy
• Eric Lightcap. Millennium: The Takeda Oncology Company. Cambridge, MA, USA.
Genome-wide screens to better understand inhibitors of enzymes within the ubiquitin-proteasome system
• Adrian Wiestner. Hematology Branch, NHLBI. Bethesda, USA.
Clinical and translation studies on proteasome inhibition in lymphoma
Organizing Committee
Rosa Farràs. Centro de Investigación Príncipe Felipe,
Valencia, Spain.
Jaime Font de Mora. Centro de Investigación Príncipe Felipe,
Valencia, Spain.
Erwin Knecht. Centro de Investigación Príncipe Felipe,
Valencia, Spain.
Timothy Thomson. Instituto de Biología Molecular- CSIC,
Barcelona, Spain.
Marc Piechaczyk. Institut de Génétique Moléculaire de Montpellier
CNRS, Montpellier, France.
Manuel Rodríguez. CiC-Biogune, Bilbao, Spain.
Symposium secretariat
Cátedra Santiago Grisolía
Fundación Ciudad de las Artes y las Ciencias –
Comunitat Valenciana
Paseo de la Alameda, 42-B, 1.º - 1.ª
46023 Valencia, Spain
Telephone: 0034 96 197 4670
Fax: 0034 96 197 4598
E-mail: catedrasg@cac.es
FOR MORE INFORMATION ABOUT THIS EVENT PLEASE: www.fundacioncac.es/catedrasg |
| |
|
Workshop Venue
The International Symposium on Intracellular Proteolysis and Cancer will be held in the Santiago Grisolía Auditorium at the Museo de las Ciencias Príncipe Felipe of Valencia (Spain). The museum, designed by Valencian architect Santiago Calatrava, and with an auditorium of 2.800 square metres, provides the perfect venue for this symposium.
These emblematic projects have turned Valencia, with its heritage of over two thousand years of history, into a most modern city. The city is easily accessible by road, rail, sea and air. Its culture, cuisine and academic tradition along with its location on the Mediterranean coast and its pleasant climate, make the city the ideal setting for this symposium.
Santiago Grisolía Auditorium
Science Museum Príncipe Felipe
City of Arts and Sciences
Av. Autopista del Saler, 7
46013 Valencia, Spain
How to arrive to the venue
The Science Museum Principe Felipe, which is one of the buildings of the City of Arts and Sciences (a cultural entertainment centre with stunning architecture), is in the dry river bed Turia.
- By bus
The following EMT buses go to the venue: 1, 19, 35, 40 y 95. The trip from the city center takes about 15 minutes.
For more information, please visit www.emtvalencia.es
- By taxi
From the city center it can easily reach by taxi in 10 minutes. It costs 6/10€
City of Valencia
Valencia is a vibrant, cosmopolitan city on the Mediterranean coast and has more than 800.000 inhabitants, making it the third largest city in Spain. It is a pleasant historical city with modern tourist infrastructures and enjoys a good climate, attractive surroundings and offers a wide variety of cultural and leisure events. There are several sandy beaches and other places of interest within easy reach of the city. To discover Valencia, please visit http://www.turisvalencia.es
Valencia Interactive Map |
| |
Visas
Some participants may require visas in order to enter to Spain. Please check with your travel agent if a visa is required.
Language
The lectures will be given in English.
IMPORTANT INFORTATION:
Registration fee
Up to September 10th 2011: 250 €
After September 10th 2011: 350 €
The registration fee includes scientific sessions, symposium materials, lunches and coffee breaks.
A certificate of attendance will be given to all participants.
Welcome Dinner on October 27th: 45€ per person. (Deadline to confirm attendance and make payment: October 19th)
Payment
Payment of registration fees should be made in Euro by bank transfer:
Account name: Fundación Ciudad de las Artes y las Ciencias
Bank details: BANCAJA. Av. Cataluña 6. 46021 Valencia, Spain.
Swift code for international bank transfers:
IBAN: ES48 2077 0737 74 3100345279
BIC: CVALESVVXXX
Account number for Spanish bank transfers:
2077 0737 74 3100345279
Once the bank transfer has been made, a copy of the bank transfer must be sent by e-mail: catedrasg@cac.es or fax (0034 96 197 45 98) indicating the participant’s name before that the symposium starts.
Note: Your registration will be only considered upon receiving the full payment. |
| |
Travel and Accomodation
By our travel agency
To make your travel arrangements you can put in contact with our travel agency Viajes Iberia. The agency has booked rooms in several hotels within walking distance of the venue. Shared rooms are available. Information can be obtained from:
Ms. Matilde García-Conde
Tel.: 0034 96 353 61 65
Fax: 0034 96 394 06 06
E-mail: valencia.hernancortes23@viajesiberia.com
On your own
Travel information: how to arrive to Valencia
- By air
The airport (Manises International Airport) is about 8 km from the city centre.
To see information about all the airline companies operating out of this airport, please click here
How to get from the Airport to Valencia city:
- By bus: click here
- A taxi from the airport will cost approximately 25/30 Euros.
- Underground: Lines 3 and 5. Every 10-20 minutes approx. More information about timetable and fares, please visit www.metrovalencia.com
- By train
Valencia North Station is situated in the city centre. For information on timetable and fares, please visit www.renfe.es
- By coach
Valencia coach station is located on the bank of the former course of the River Túria. This is the stopping place for regular services arriving from all over Spain. For further information, please visit www.turisvalencia.es
- By car
The AP-7 Motorway runs down the East Coast of Spain connecting Valencia to the main European Motorway network and to A-23 Sagunto-Somport and the A-3 Madrid-Valencia dual Carriageway.
- By sea
Although Valencia is principally an industrial port it also operates a frequent ferry service to the Balearic Islands and is the starting point for many Mediterranean Cruises. It is well connected to the city centre by a number of frequent bus routes. For more information, please visit www.valenciaport.com
Accommodation
Please, click here to see a list of the nearest hotels to the meeting venue.
For more information, please visit www.turisvalencia.es
|
| |
Our Sponsors are:
|
|
|
| Future Events 2012 |
|  The 1st FEBS
SPECIAL MEETING
on Ubiquitin Proteasome System &
Protein Quality Control
in Health and Disease
 |
November 14-16, 2012
Venue Pine Bay Holiday Resort
Camlimani, Kusadasi (Aydin), TURKEY
|
Host Institution : Ege University Faculty of Pharmacy
Biochemistry Department
Bornova, 35100, Izmir, Turkey
  |
Organizers:
Petek Ballar
Ege University,
Izmir, Turkey.
Michael Glickman
The Technion
Haifa, Israel.
Thomas Sommer,
Max-Delbrück-Center for Molecular Medicine
Berlin, Germany.
Devrim Gözüaçik,
Sabanci University,
Istanbul, TURKEY.
Manuel Rodríguez,
CiC bioGUNE
Bilbao, Spain,
|
Our Invited Speakers:
Aaron Ciechanover,
Technion-Israel Institute of Technology, ISRAEL
Alexander Buchberger,
University of Würzburg, GERMANY
Allan M. Weissman,
National Cancer Institute at Frederick, MD USA
Ana Maria Cuervo,
Albert Einstein College of Medicine, NY, USA
Anne Bertolotti,
MRC Laboratory of Molecular Biology, Cambridge, UK.
Ashraf Brik,
Ben-Gurion University, Beer Sheva, ISRAEL
Bruno Andre,
Université Libre de Bruxelle, Gosselies BELGIUM
David Fushman,
University of Maryland, MD, USA
David Komander,
MRC Laboratory of Molecular Biology, Cambridge, UK
David Rubinzstein,
Cambridge Institute for Medical Research , UK
Edward Morris,
The Institute of Cancer Research, London, UK
Harald Stenmark,
Oslos University Hospital, Institute for Cancer Research, NORWAY
Jeffrey L. Brodsky,
University of Pittsburgh, PA USA
Judith Frydman,
Stanford University, CA, USA
Paul Lehner,
Cambrigde Cancer Center, UK
Rosine Haguenauer,
Institut Jaques Monod /Université Paris Diderot, FRANCE
Scott D. Emr,
Cornell University, NY, USA
Shengyun Fang,
University of Maryland, Baltimore,MD, USA
Sylvie Urbé,
University of Liverpool, Institute of Translational Medicine, UK
Stefan Jentsch,
Max Planck Institute of Biochemistry,GERMANY
Thorsten Hoppe,
University of Cologne, Institute for Genetics, GERMANY
Zevi Elazar.
Weizmann Institute of Science Rehovot, ISRAEL |
About this meeting
Newly synthesized proteins undergo folding, assembly, and posttranslational modifications for their proper functions. All these steps are strictly controlled by the Protein Quality Control Mechanism (QCM). QCM distinguishes between properly modified and improperly modified proteins and ensues retention and degradation of misfolded, unfolded or unassembled. The organised intracellular degradation of these proteins either by ubiquitin-proteasome system (UPS) or autophagy is crucial to maintain cell physiology and cellular homeostasis. Defects on molecular mechanisms controlling or taking a part in these processes have been implicated in pathogenesis of many diseases, such as cancer, cystic fibrosis, diabetes and neurodegenerative diseases. This meeting has a very timely topic, because it comprises a very broad and competitive field that brings together studies of many scientists from basic and translational sciences.
INPROTEOLYS network organizes annual meetings on different aspects of intracellular proteolysis in order to facilitate the interaction, collaboration and exchange of “know-how” between researchers and students working in this topic. The seventh meeting will be covering topics in Protein Quality Control and Ubiquitin Systems in health and disease and held in Izmir, Turkey (the first meeting outside of Spain). This meeting has a unique feature that gives chance to scientists working on different aspects of protein quality control and ubiquitin system to meet each other and exchange knowledge. For example during the session of autophagy, the ubiquitin proteasome system involvement and possible crosstalk between autophagy and UPS will be discussed.
One of the major objectives of the meeting is to attract young researchers by giving them the chance to meet and develop links with the widely acknowledged experts in the field. This will be established by presentations during poster sessions and short talks in every session.
We expect more than 120 young scientists to attend our meeting. By having high quality plenary lectures by well-known scientists and short talks together with affordable registration fee and “accommodation + meal package” we believe 7th Inproteolys Meeting will have the highest number of submission for participation. Acceptance will be based upon the quality and relevance of the submissions. The majority of participants will come from the following countries: Australia, France, Germany, Spain, Italy, Israel, USA and UK.
We want to have the meeting to focus on discussions among the scientists of the field to further international scientific collaboration, but as importantly, to expose graduate students to the beauty of basic science and research. In order to attract more young scientists from neighborhood countries (considering the economical situation of today) to fulfill the requirement of the FEBS Special Meeting, we know that it is vital to have affordable registration fee and travel grants. As such the meeting will be heavily subsidized for students, local and international, and all students will be given ample opportunity to present their research and to approach invited speakers at meals, round tables, poster sessions and informal discussions.
|
Proposed content of the sessions
Session I: Protein Quality Control and ubiquitin
Session II: Protein degradation by ubiquitin proteasome system
Session III: Ubiquitin & Signaling & Membrane associated processes
Session IV: Protein misfolding & aggregates
Session V: Autophagy
Session VI: Novel aspects of structural biology in ubiquitin systems
|
About our Venue
The meeting will be held in the Pine Bay Resort, Kusadasi, Turkey. Kusadasi is located close to Izmir, the third biggest city of Turkey. Its culture, cuisine and academic tradition and pleasant climate make the city ideal for this meeting.
In the 10th century BC "12 Ionian Cities "-Samos, Khios, Miletos, Priene, Ephesus, Teos, Erythrai, Priena, Klazonemi, Lebedos, Phokaia, Colophon, Smyrna, were established around Kusadasi and reputed as the most developed cities of that age. Ancient city Ephesus and House of Virgin Mary are some of the nearby historical locations.
Pine Bay Resort is one the main meeting organization centers in Izmir, Turkey. It has four different meeting rooms with appropriate size and technical support and also a large hall area which is designed for poster presentations. The Resort has offered no charge for rental of meeting room when meeting is organized in this hotel. Furthermore, they offered 100 euros/person/day (single accommodation) including accommodation, breakfast, lunch and dinner. The package also covers 2 coffee breaks/day.
- General characteristics: Capacity for 400 seats - Classroom-type layout - Hall: reception and
authorization delivery point. Its 525 sq/m surface area is also ideal for coffee breaks and cocktails. The hall is also ideal for poster presentations. The poster boards will be supplied by the Resort.
- Technical characteristics: Working table services – Cordless and fixed microphones –Cinevision –Loudspeaker – Overhead projectors –Fixed and portable screens – Video player |
|
STUDENTS FELLOWSHIPS
Please wait for information: |
Visas
wait for information
Language
The lectures will be given in English.
IMPORTANT INFORTATION:
Registration fee
wait for information
Payment
wait for information
Note: Your registration will be only considered upon receiving the full payment.
Travel and Accomodation
wait for information
The Young Investigator award will be given by:
Please wait for information: |
This space is dedicated to our sponsors
Our Sponsors are: |
|
|
Past Events |
|
|
|
EMBO Worshop
Proteolysis and Neurodegeneration
(5th INPROTEOLYS meeting) |
|
| |
Protein destruction determines a wide variety of cellular functions in the CNS. Dysfunctions of these processes are at the origin of many pathologies including most neurodegenerative diseases. Parkinson, Alzheimer and Huntington diseases represent the largest proportion of fatal ailments for mankind, and the three of them have no cure at present. During this meeting, subjects related to the role of proteolysis in normal and degenerated neuronal processes will be discussed. In particular protein destruction by autophagy and the ubiquitin-proteasome pathways will be covered in this symposium. The selected speakers are international experts in the field at the zenith of their professional careers. In addition, the event has been designed to attract young researchers giving them the opportunity to develop long term links with their peers. Also, the program is oriented towards the in-depth debate of frontier issues and the development of new strategies. In this way, we expect to contribute to the consolidation of this relevant field whose clinical implications have a wide social interest.
Final Program (Click Here)
Registration (Click Here)
Payment (Click Here)
|
| |
May 4-7, 2010
Fundacion Ramon Areces, Madrid |
| |
|
Workshop Venue
The Ramon Areces Foundation is a non-profit organisation created in 1976 to broadly encourage scientific and technical research in Spain, as well as education and culture in general, values that the institution considers to be the main driving forces for progress and modernity in society. The institution carries out activities throughout the whole of Spain in the fields of life and material sciences, and social sciences and humanities, areas in which it promotes scientific research, contributes to training human resources and disseminates knowledge. The institution has its own programme for each of these areas: National competitions for research aid; scholarships for postgraduate studies abroad; and scientific, socio-economic and cultural dissemination programmes. |
| |
|
| |
Madrid is a surprising and a fascinating city famous for its zest for life. Architecturally is a incredible city to explore and take in the atmosphere, especially around the Old Madrid of the Habsburgs including Puerta del Sol and Plaza Mayor. Culturally, the art scene is right up there with the Prado remaining the city's major cultural attraction and Picasso's 'Guernica' in the Reina-Sofia being the number one exhibit. Madrid is also a great place to see the traditional Spanish arts. For more information please visit the following links:
http://www.museodelprado.es/en/
http://www.museoreinasofia.es/index_en.html
http://www.museothyssen.org//THYSSEN/home
http://www.spanish-fiestas.com/madrid/
http://www.madrid-guide-spain.com/ |
| |
Organizers:
Alberto Ferrús, Instituto Cajal, CSIC.
Manuel S. Rodríguez, CICbioGUNE
Patricia Boya, Centro de Investigaciones Biológicas, CSIC.
Jose Castaño, Universidad Autónoma de Madrid.
David Rubinsztein, Cambridge Institute for Medical Research
Wiep Scheper, Universiteit Van Amsterdam
Ana Ma. Cuervo, Albert Einstein College of Medicine (USA) |
| |
SPEAKERS
Sam Sinsodia Keiji Tanaka
Ana Maria Cuervo Ron Kopito
Noboru Mishuzima Tiago Fleming Outeiro
Francesco Cecconi Wiep Scheper
Patricia Boya Santiago Rodríguez de Córdoba
David Rubinsztein José G. Castaño
Ralph Nixon Paul Fraser
Michael Coleman Nancy Bonini
Tabrizi Sarah Alberto Ferrus |
| |
The EMBO Young Investigator award lecture will be given by: Michele Vendruscolo
Please note:
-Poster Prize will be attributedby EMBO and ENZO Life Sciences.
-10 registration fee fellowships will be attributed to young scientists. Interested candidates should send an email to: mrodriguez@cicbiogune.es. Please attach your CV and abstract you would like to present. |
|
|
Past Events 2010 |
ZOMES VI
Expanding the PCI family beyond
proteasome, CSN and eIF3 complexes
a joint meeting ZOMES and
INPROTEOLYS network
October 4-7, 2010
Safed (Galilee) ISRAEL |
| |
Organizers:
Dany Chamovitz (Tel Aviv)
Jun Ya Kato (Japan)
Pardi Ruggero (Italy)
Michael Glickman (Israel) INPROTEOLYS
Manuel S Rodriguez (Spain) INPROTEOLYS
Dimitris Xirodimas (UK) INPROTEOLYS |
| |
ABOUT ZOMES
The ZOMES meetings were initiated in 1999 with ZOMES I, which was held in Israel (get more info). ZOMES VI, which will be held in October 2010 in Israel (http://www.weizmann.ac.il/conferences/ZOMESVI/). This international meeting is apart of an International series that focuses on the three "PCI" complexes, the proteasome, the COP9 signalosome, and eIF3. In the coming meeting we would like to broaden the field and highlight additional associated complexes that contain so called "orphaned PCI subunits" or interact with the three canonical Zomes. Your work on Proteasome would fit perfectly with these topics and objectives. The previous Zomes meetings (I - V) took place in Israel, Turkey, Germany, USA, Japan, and now Zomes VI is back in
Israel in the historical and exotic city of Safed. For Zomes VI we have a very nice line up of confirmed speakers, with more to come from abstracts and registrants. We are very fortunate to have two Nobel Laureate ZOME researchers for the opening talks which will be part of the banquet dinner (Avram Hershko and Ada Yonath).
ABOUT THIS MEETING
The goal of our symposia is to bring together researchers from diverse fields, who normally have no venue to meet, in order to initiate joint efforts for studying the functioning of these complexes. ZOMES meetings are unique in that scientists such cancer researchers and plant scientists interact freely and exchange ideas, providing a forum for cross-fertilization which is absent in most specialized meetings. |
|
SPEAKERS
Avram Hershko Ada Yonath
Ruggedo Pardi JunYa Kato
Michael Glickman Danny Chamovitz
Manuel Rodriguez Dimitris Xirodimas
Michal Sharon Carol Robinson
Ning Wei Dieter Wolf
Wolfgang Dubiel Ed Morris
Claus Schwechheimer Yossi Shilo
Michael Nauman Dan Finley
Albrecht Von Arnim Elah Pick
Lionel Pintard Joel Hirsch
Daniel Kornizter Kay hofmann |
| |
|
|
Past Activities
Our first training course will he hosted by the CICbioGUNE, Bilbao,Basque Country, Spain, from the 1st to 7th of september 2008. A limited number of PhD students and post-doctorals have been accepted. To see pictures , please (click here).
This WEB page was fully sponsored by the Basque Country Government.
|
|
